osCommerce stores work perfectly with Nochex so that won't be a problem
Leave it with me Mark and I'll put together some information for you tomorrow morning that tells you more about how everything works. Will send you that by PM (Private Message).
To summarise though, once the site is up and running (as Dave said, the building side of it isn't so straight forward, but that's not something you need to worry about) it's very, very easy to use.
Cheers,
Ali.